Matr3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Matr3
matrin 3
MGI:1298379

40 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Matr3^em1Tcp/Matr3^em1Tcp C57BL/6J-Matr3^em1Tcp	abnormal neuromuscular synapse morphology	J:298091
	astrocytosis	J:298091
	ataxia	J:298091
	axon degeneration	J:298091
	axonal spheroids	J:298091
	decreased body size	J:298091
	decreased body weight	J:298091
	decreased grip strength	J:298091
	decreased skeletal muscle fiber size	J:298091
	decreased vertical activity	J:298091
	impaired contextual conditioning behavior	J:298091
	impaired coordination	J:298091
	impaired cued conditioning behavior	J:298091
	impaired righting response	J:298091
	increased microglial cell activation	J:298091
	limb grasping	J:298091
	premature death	J:298091
	Purkinje cell degeneration	J:298091
	small cerebellum	J:298091
	weight loss	J:298091
Matr3^em3Tcp/Matr3^em3Tcp C57BL/6J-Matr3^em3Tcp	cyanosis	J:298091
	neonatal lethality, complete penetrance	J:298091
	respiratory distress	J:298091
Matr3^em4Tcp/Matr3^em4Tcp C57BL/6J-Matr3^em4Tcp	cyanosis	J:298091
	neonatal lethality, complete penetrance	J:298091
	respiratory distress	J:298091
Matr3^em5Tcp/Matr3^em5Tcp C57BL/6J-Matr3^em5Tcp	cyanosis	J:298091
	neonatal lethality, complete penetrance	J:298091
	respiratory distress	J:298091
Matr3^{Gt(RRR075)Byg}/Matr3⁺ either: (involves: 129 * 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * FVB/N)	abnormal aortic arch morphology	J:220876
	abnormal heart apex morphology	J:220876
	abnormal heart left ventricle outflow tract morphology	J:220876
	abnormal heart valve morphology	J:220876
	aorta coarctation	J:220876
	aortic arch hypoplasia	J:220876
	bicuspid aortic valve	J:220876
	bicuspid pulmonary valve	J:220876
	double outlet right ventricle, Taussig bing type	J:220876
	double outlet right ventricle, ventricular defect committed to aorta	J:220876
	interrupted aortic arch	J:220876
	muscular ventricular septal defect	J:220876
	patent ductus arteriosus	J:220876
	perimembraneous ventricular septal defect	J:220876
	ventricular septal defect	J:220876
Matr3^{Gt(RRR075)Byg}/Matr3^{Gt(RRR075)Byg} either: (involves: 129 * 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * C57BL/6J * FVB/N)	embryonic lethality before implantation, incomplete penetrance	J:220876
	embryonic lethality between implantation and placentation, complete penetrance	J:220876

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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