Clec4d Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Clec4d
C-type lectin domain family 4, member d
MGI:1298389

31 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Clec4d^tm1.1Cfg/Clec4d^tm1.1Cfg involves: C57BL/6	decreased B cell proliferation	J:217719
	decreased T cell proliferation	J:217719
	extramedullary hematopoiesis	J:217719
	normal immune system phenotype	J:203221
	increased B cell number	J:217719
	increased interferon-gamma secretion	J:203221
	increased interleukin-6 secretion	J:203221
	increased interleukin-10 secretion	J:203221
	increased interleukin-17 secretion	J:203221
	increased mature B cell number	J:217719
	increased susceptibility to bacterial infection	J:203221
	increased susceptibility to bacterial infection induced morbidity/mortality	J:203221
	increased tumor necrosis factor secretion	J:203221
	lung inflammation	J:203221
Clec4d^tm1.1Shoy/Clec4d^tm1.1Shoy involves: 129P2/OlaHsd * C57BL/6	abnormal antigen presentation	J:203159
	abnormal chemokine secretion	J:203159
	abnormal immune serum protein physiology	J:203159
	abnormal immune system physiology	J:203159
	abnormal interferon-gamma secretion	J:203159
	abnormal interleukin-17 secretion	J:203159
	abnormal response to infection	J:203159
	abnormal thymus morphology	J:203159
	decreased circulating interleukin-17 level	J:203159
	decreased dendritic cell number	J:203159
	decreased IgG level	J:203159
	decreased physiological sensitivity to xenobiotic	J:203159
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:203159
	decreased susceptibility to type IV hypersensitivity reaction	J:203159
	decreased susceptibility to xenobiotic induced morbidity/mortality	J:203159
	decreased tumor necrosis factor secretion	J:203159
	granulomatous inflammation	J:203159
	lung inflammation	J:203159

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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