Sncg Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sncg
synuclein, gamma
MGI:1298397

27 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sncg^tm1Vlb/Sncg^tm1Vlb B6.129P2-Sncg^tm1Vlb	normal behavior/neurological phenotype	J:86439, J:92213
	decreased dopaminergic neuron number	J:92213
	decreased susceptibility to dopaminergic neuron neurotoxicity	J:92213
	normal nervous system phenotype	J:86439, J:92213
Tg(Thy1-Sncg)HvP36Putt/0 C57BL/6-Tg(Thy1-Sncg)HvP36Putt	abnormal motor coordination/balance	J:147580
	amyloidosis	J:147580
	astrocytosis	J:147580
	decreased motor neuron number	J:147580
	impaired coordination	J:147580
	short stride length	J:147580
Tg(Thy1-Sncg)HvP36Putt/? C57BL/6-Tg(Thy1-Sncg)HvP36Putt	abnormal dorsal spinal root morphology	J:185793
	abnormal myelin sheath morphology	J:185793
	abnormal sciatic nerve morphology	J:185793
	abnormal trigeminal nerve morphology	J:185793
	abnormal ventral spinal root morphology	J:185793
	astrocytosis	J:185793
	decreased motor neuron number	J:185793
	gliosis	J:185793
	microgliosis	J:185793
	normal nervous system phenotype	J:185793
	neuron degeneration	J:185793
Tg(Thy1-Sncg)HvP36Putt/Tg(Thy1-Sncg)HvP36Putt C57BL/6-Tg(Thy1-Sncg)HvP36Putt	abnormal gait	J:147580
	abnormal motor coordination/balance	J:147580
	abnormal nervous system morphology	J:147580
	amyloidosis	J:147580
	astrocytosis	J:147580
	decreased motor neuron number	J:147580
	hunched posture	J:147580
	impaired balance	J:147580
	impaired coordination	J:147580
	impaired righting response	J:147580
	limb grasping	J:147580
	paralysis	J:147580
	paresis	J:147580
	premature death	J:147580
	short stride length	J:147580

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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