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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sncg
synuclein, gamma
MGI:1298397
27 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Sncgtm1Vlb/Sncgtm1Vlb
B6.129P2-Sncgtm1Vlb 		normal behavior/neurological phenotype J:86439, J:92213
decreased dopaminergic neuron number J:92213
decreased susceptibility to dopaminergic neuron neurotoxicity J:92213
normal nervous system phenotype J:86439, J:92213
Tg(Thy1-Sncg)HvP36Putt/0
C57BL/6-Tg(Thy1-Sncg)HvP36Putt 		abnormal motor coordination/balance J:147580
amyloidosis J:147580
astrocytosis J:147580
decreased motor neuron number J:147580
impaired coordination J:147580
short stride length J:147580
Tg(Thy1-Sncg)HvP36Putt/?
C57BL/6-Tg(Thy1-Sncg)HvP36Putt 		abnormal dorsal spinal root morphology J:185793
abnormal myelin sheath morphology J:185793
abnormal sciatic nerve morphology J:185793
abnormal trigeminal nerve morphology J:185793
abnormal ventral spinal root morphology J:185793
astrocytosis J:185793
decreased motor neuron number J:185793
gliosis J:185793
microgliosis J:185793
normal nervous system phenotype J:185793
neuron degeneration J:185793
Tg(Thy1-Sncg)HvP36Putt/Tg(Thy1-Sncg)HvP36Putt
C57BL/6-Tg(Thy1-Sncg)HvP36Putt 		abnormal gait J:147580
abnormal motor coordination/balance J:147580
abnormal nervous system morphology J:147580
amyloidosis J:147580
astrocytosis J:147580
decreased motor neuron number J:147580
hunched posture J:147580
impaired balance J:147580
impaired coordination J:147580
impaired righting response J:147580
limb grasping J:147580
paralysis J:147580
paresis J:147580
premature death J:147580
short stride length J:147580
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory