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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sucla2
succinate-Coenzyme A ligase, ADP-forming, beta subunit
MGI:1306775
13 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Sucla2Gt(IST10208H1)Tigm/Sucla2+
involves: 129S/SvEv * C57BL/6N 		abnormal mitochondrial physiology J:241325
abnormal oxidative phosphorylation J:241325
normal cellular phenotype J:241325
decreased hepatocyte mitochondrial DNA content J:241325
decreased mitochondrial DNA content J:241325
decreased myocardial fiber mitochondrial DNA content J:241325
increased circulating carnitine level J:241325
Sucla2Gt(IST10208H1)Tigm/Sucla2Gt(IST10208H1)Tigm
involves: 129S/SvEv * C57BL/6N 		prenatal lethality J:241325
Sucla2Gt(SAbetageo)1Bhg/Sucla2+
involves: 129S6/SvEvTac * C57BL/6 		increased mitochondrial DNA content J:213453
Sucla2Gt(SAbetageo)1Bhg/Sucla2Gt(SAbetageo)1Bhg
involves: 129S6/SvEvTac * C57BL/6 		abnormal mitochondrial morphology J:213453
abnormal mitochondrial physiology J:213453
abnormal placenta morphology J:213453
decreased fetal size J:213453
decreased mitochondrial DNA content J:213453
increased mitochondrial DNA content J:213453
perinatal lethality, complete penetrance J:213453
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory