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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dio3
deiodinase, iodothyronine type III
MGI:1306782
19 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dio3tm1Dmst/Dio3tm1Dmst
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: C57BL/6 * DBA 		abnormal response to injury J:218350
normal growth/size/body region phenotype J:218350
normal homeostasis/metabolism phenotype J:218350
increased circulating thyroxine level J:218350
increased circulating triiodothyronine level J:218350
increased hepatocyte proliferation J:218350
normal liver/biliary system phenotype J:218350
Dio3tm1Stg/Dio3tm1Stg
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal pituitary hormone level J:105434
abnormal thyroid hormone level J:105434
decreased circulating thyroid-stimulating hormone level J:105434
decreased circulating thyroxine level J:105434
decreased circulating triiodothyronine level J:105434
increased circulating thyroid-stimulating hormone level J:105434
increased triiodothyronine level J:105434
maternal imprinting J:80434
perinatal lethality, incomplete penetrance J:105434
postnatal growth retardation J:105434
prenatal lethality, incomplete penetrance J:105434
reduced fertility J:105434
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory