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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Apaf1
apoptotic peptidase activating factor 1
MGI:1306796
6 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Aifm1Hq/Aifm1Hq
Apaf1Gt(IRESBetageo)XIX18Pgr/Apaf1Gt(IRESBetageo)XIX18Pgr
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		decreased neuron apoptosis J:98103
Apaf1Gt(IRESBetageo)XIX18Pgr/Apaf1Gt(IRESBetageo)XIX18Pgr
Aifm1tm2Pngr/Y
Foxg1tm1(cre)Skm/Foxg1+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		abnormal mitochondrial physiology J:112874
decreased neuron apoptosis J:112874
increased neuron apoptosis J:112874
thickened cerebral cortex J:112874
Apaf1tm1Mak/Apaf1tm1Mak
Rb1tm1Tyj/Rb1tm1Tyj
Tg(Rb1)1Blg/0
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 		increased cochlear hair cell number J:98518
increased vestibular hair cell number J:98518
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory