Ltb4r1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ltb4r1
leukotriene B4 receptor 1
MGI:1309472

20 phenotypes from 3 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ltb4r1^tm1Adl/Ltb4r1^tm1Adl involves: 129S4/SvJae * C57BL/6	abnormal leukocyte adhesion	J:63873
	abnormal leukocyte migration	J:63873
	abnormal macrophage physiology	J:63873
	abnormal neutrophil physiology	J:63873
	impaired eosinophil recruitment	J:63873
	impaired neutrophil chemotaxis	J:63873
Ltb4r1^tm1Bodd/Ltb4r1^tm1Bodd either: (involves: 129S4/SvJaeSor * BALB/c ) or (involves: 129S4/SvJaeSor * C57BL/6)	decreased susceptibility to induced arthritis	J:163271
	impaired neutrophil chemotaxis	J:163271
Ltb4r1^tm1Bodd/Ltb4r1^tm1Bodd involves: 129S4/SvJaeSor	decreased susceptibility to induced arthritis	J:131779
Ltb4r1^tm1Bodd/Ltb4r1^tm1Bodd involves: 129S4/SvJaeSor * C57BL/6	decreased susceptibility to autoimmune disorder	J:108446
Ltb4r1^tm1Tksh/Ltb4r1^tm1Tksh B6.Cg-Ltb4r1^tm1Tksh	abnormal cytokine secretion	J:118995
	abnormal hormone level	J:118995
	abnormal respiratory system physiology	J:118995
	decreased airway responsiveness	J:118995
	decreased cell proliferation	J:118995
	decreased eosinophil cell number	J:118995
	decreased IgE level	J:118995
	decreased susceptibility to type I hypersensitivity reaction	J:197334
	edema	J:197334
	lung inflammation	J:118995
Ltb4r1^tm1Tksh/Ltb4r1^tm1Tksh C.Cg-Ltb4r1^tm1Tksh	abnormal mast cell physiology	J:133998
Ltb4r1^tm1Tksh/Ltb4r1^tm1Tksh involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj	abnormal granulocyte physiology	J:118995

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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