Rtf1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rtf1
RTF1, Paf1/RNA polymerase II complex component
MGI:1309480

16 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rtf1^{tm1a(KOMP)Wtsi}/Rtf1^{tm1a(KOMP)Wtsi} B6Brd;B6Dnk;B6N-Rtf1^{tm1a(KOMP)Wtsi} Tyr^c-Brd/Wtsi	preweaning lethality, complete penetrance	J:211773
Rtf1^{tm1c(KOMP)Wtsi}/Rtf1^{tm1c(KOMP)Wtsi} A1cf^{Tg(Myh6-cre/Esr1)1Jmk}/A1cf⁺ involves: C57BL/6N FVB/N	abnormal heart echocardiography feature	J:338311
	abnormal intercalated disk morphology	J:338311
	cardiac fibrosis	J:338311
	congestive heart failure	J:338311
	decreased heart left ventricle muscle contractility	J:338311
	decreased heart left ventricle wall thickness	J:338311
	decreased heart right ventricle wall thickness	J:338311
	decreased heart ventricle muscle contractility	J:338311
	dilated cardiomyopathy	J:338311
	dilated heart left ventricle	J:338311
	dilated heart right ventricle	J:338311
	dilated heart ventricle	J:338311
	myocardial fiber disarray	J:338311
	premature death	J:338311
	thin ventricular wall	J:338311

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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