Cdc7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cdc7
cell division cycle 7
MGI:1309511

25 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cdc7^{tm1.1(KOMP)Vlcg}/Cdc7⁺ C57BL/6N-Cdc7^{tm1.1(KOMP)Vlcg}/Tcp	abnormal skin morphology	J:211773
	decreased neutrophil cell number	J:211773
	increased lymphocyte cell number	J:211773
Cdc7^{tm1.1(KOMP)Vlcg}/Cdc7^{tm1.1(KOMP)Vlcg} C57BL/6N-Cdc7^{tm1.1(KOMP)Vlcg}/Tcp	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Cdc7^tm1Hmas/Cdc7^tm1Hmas involves: 129S/Sv * C57BL/6	embryonic lethality between implantation and somite formation, complete penetrance	J:76497
Cdc7^tm1Hmas/Cdc7^tm1Hmas involves: 129S/Sv * C57BL/6	inner cell mass degeneration	J:76497
Cdc7^tm1Hmas/Cdc7^tm1Hmas Tg(EF1A-Cdc7)DKO28Hmas/0 involves: 129S/Sv * C57BL/6	abnormal cell cycle	J:85942
	abnormal female reproductive system morphology	J:85942
	abnormal gametogenesis	J:85942
	abnormal male reproductive system morphology	J:85942
	abnormal seminiferous tubule morphology	J:85942
	absent ovarian follicles	J:85942
	arrest of male meiosis	J:85942
	curly tail	J:85942
	decreased body size	J:85942
	decreased DNA replication	J:85942
	normal immune system phenotype	J:85942
	multinucleated giant male germ cells	J:85942
	postnatal lethality, incomplete penetrance	J:85942
	prenatal lethality, incomplete penetrance	J:85942
	small ovary	J:85942
	small testis	J:85942
Cdc7^tm1Hmas/Cdc7^tm1Hmas Tg(EF1A-Cdc7)DKO28Hmas/Tg(EF1A-Cdc7)DKO28Hmas involves: 129S/Sv * C57BL/6	no abnormal phenotype detected	J:85942

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24