Itm2b Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Itm2b
integral membrane protein 2B
MGI:1309517

7 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Itm2b^tm1.1Ldad/Itm2b⁺ Tg(APPswe,PSEN1dE9)85Dbo/0 involves: 129 * C3H * C57BL/6	abnormal nervous system physiology	J:138796
Itm2b^tm2.1Ldad/Itm2b⁺ B6.129-Itm2b^tm2.1Ldad	abnormal object recognition memory	J:167154
	impaired contextual conditioning behavior	J:167154
	impaired spatial working memory	J:167154
	normal nervous system phenotype	J:167154
	reduced long-term potentiation	J:167154
Itm2b^tm2.1Ldad/Itm2b⁺ Tg(Camk2a-ITM2B)8.4Ldad/0 B6.Cg-Itm2b^tm2.1Ldad Tg(Camk2a-ITM2B)8.4Ldad	normal behavior/neurological phenotype	J:167154
Itm2b^tm2.1Ldad/Itm2b^tm2.1Ldad B6.129-Itm2b^tm2.1Ldad	normal nervous system phenotype	J:155411

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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