Ppp1r12a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ppp1r12a
protein phosphatase 1, regulatory subunit 12A
MGI:1309528

21 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ppp1r12a^em1Sfsh/Ppp1r12a⁺ Tg(Myh11-icre/ERT2)1Soff/0 involves: C57BL/6J * FVB/N	abnormal blood vessel physiology	J:230106
Ppp1r12a^tm1Mito/Ppp1r12a^tm1Mito involves: 129X1/SvJ * C57BL/6	embryonic lethality between implantation and somite formation, complete penetrance	J:100069
Ppp1r12a^tm1Mzhu/Ppp1r12a^tm1Mzhu Tg(Acta2-cre)#Xya/0 involves: 129S6/SvEvTac * C57BL/6 * CBA	abnormal ileum morphology	J:207752
	abnormal interstitial cell of Cajal morphology	J:207752
	abnormal intestine morphology	J:207752
	abnormal jejunum morphology	J:207752
	abnormal muscle contractility	J:207752
	abnormal muscle electrophysiology	J:207752
	abnormal small intestine morphology	J:207752
	abnormal smooth muscle morphology	J:207752
	normal digestive/alimentary phenotype	J:207752
	distended abdomen	J:207752
	enlarged duodenum	J:207752
	enlarged ileum	J:207752
	enlarged stomach	J:207752
	enlarged urinary bladder	J:207752
	increased systemic arterial systolic blood pressure	J:207752
	intestinal hypoperistalsis	J:207752
	ischuria	J:207752
	premature death	J:207752
	small intestinal inflammation	J:207752

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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