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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Slfn2
schlafen 2
MGI:1313258
17 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Slfn2m1Btlr/Slfn2m1Btlr
C57BL/6J-Slfn2m1Btlr 		abnormal leukocyte physiology J:158985
abnormal nitric oxide homeostasis J:158985
abnormal T cell activation J:158985
abnormal T cell proliferation J:158985
decreased CD4-positive, alpha-beta T cell number J:158985
decreased CD8-positive, alpha-beta T cell number J:158985
decreased monocyte cell number J:158985
decreased T cell proliferation J:158985
increased neutrophil cell number J:158985
increased susceptibility to bacterial infection J:158985
increased susceptibility to bacterial infection induced morbidity/mortality J:158985
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:158985
increased susceptibility to Riboviria infection J:158985
increased T cell apoptosis J:158985
Slfn2m2Btlr/Slfn2m2Btlr
C57BL/6J-Slfn2m2Btlr 		decreased IgG level J:234262
decreased response to antigen J:234262
impaired humoral immune response J:234262
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory