Vamp2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Vamp2
vesicle-associated membrane protein 2
MGI:1313277

11 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Snap91^tm1.1Tmar/Snap91⁺ Vamp2^tm1Sud/Vamp2⁺ involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac	abnormal CNS synaptic transmission	J:228428
	decreased anxiety-related response	J:228428
	decreased body weight	J:228428
	enhanced paired-pulse facilitation	J:228428
	postnatal growth retardation	J:228428
Snap91^tm1.1Tmar/Snap91^tm1.1Tmar Vamp2^tm1Sud/Vamp2⁺ involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac	neonatal lethality, incomplete penetrance	J:228428
	postnatal lethality, complete penetrance	J:228428
	prenatal lethality, incomplete penetrance	J:228428
Vamp2^tm1Sud/Vamp2⁺ Vamp3^tm1Jpes/Vamp3^tm1Jpes involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	normal hematopoietic system phenotype	J:121010
Vamp2^tm1Sud/Vamp2^tm1Sud Vamp3^tm1Jpes/Vamp3^tm1Jpes involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	abnormal neurotransmitter secretion	J:109985
	decreased miniature excitatory postsynaptic current frequency	J:109985

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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