Aqp7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Aqp7
aquaporin 7
MGI:1314647

21 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Aqp7^tm1.1Suc/Aqp7^tm1.1Suc involves: 129S2/SvPas * C57BL/6J	abnormal kidney physiology	J:102454
	increased urine glucose level	J:102454
	normal reproductive system phenotype	J:129600
Aqp7^tm1Ask/Aqp7^tm1Ask involves: CD-1	abnormal white adipose tissue physiology	J:98734
	decreased body length	J:98734
	increased fat cell size	J:98734
	increased gonadal fat pad weight	J:98734
Aqp7^tm1Chan/Aqp7^tm1Chan involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal pancreatic islet morphology	J:125011
	normal adipose tissue phenotype	J:125011
	decreased pancreatic alpha cell number	J:125011
	decreased pancreatic beta cell number	J:125011
	decreased PP cell number	J:125011
	increased cellular glucose import	J:125011
	increased circulating insulin level	J:125011
	increased glycerol level	J:125011
	increased insulin secretion	J:125011
	small pancreatic islets	J:125011
Aqp7^tm1Nlsn/Aqp7^tm1Nlsn involves: 129S1/Sv * C57BL/6	decreased urine glycerol level	J:147631
Aqp7^tm1Nlsn/Aqp7^tm1Nlsn involves: 129S1/Sv * C57BL/6N	abnormal sperm physiology	J:145790
Aqp7^tm1Tfun/Aqp7^tm1Tfun B6N.129X1-Aqp7^tm1Tfun	decreased circulating glycerol level	J:95278
	hypoglycemia	J:95278
	increased glycerol level	J:95278

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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