Hipk2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hipk2
homeodomain interacting protein kinase 2
MGI:1314872

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Hipk1^tm1Hko/Hipk1⁺ Hipk2^tm1Hko/Hipk2^tm1Hko involves: C57BL/6	abnormal neural tube morphology	J:106931
	decreased cellular sensitivity to ultraviolet irradiation	J:106931
	embryonic lethality during organogenesis, incomplete penetrance	J:106931
Hipk1^tm1Hko/Hipk1^tm1Hko Hipk2^tm1Hko/Hipk2⁺ involves: C57BL/6	abnormal neural tube morphology	J:106931
	exencephaly	J:106931
Hipk1^tm1Hko/Hipk1^tm1Hko Hipk2^tm1Hko/Hipk2^tm1Hko involves: C57BL/6	abnormal lens vesicle development	J:106931
	abnormal neural tube morphology	J:106931
	decreased cell proliferation	J:106931
	embryonic growth retardation	J:106931
	embryonic lethality during organogenesis	J:106931
	exencephaly	J:106931
	increased apoptosis	J:106931
Hipk1^tm1Hko/Hipk1^tm1Hko Hipk2^tm1Hko/Hipk2^tm1Hko Trp53^tm2Mok/Trp53⁺ involves: 129S/SvEv * C57BL/6	exencephaly	J:106931

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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