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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hipk3
homeodomain interacting protein kinase 3
MGI:1314882
18 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Hipk3Gt(OST51087)Lex/Hipk3Gt(OST51087)Lex
involves: 129S5/SvEvBrd 		abnormal pancreatic beta cell physiology J:194563
abnormal pancreatic islet morphology J:194563
decreased insulin secretion J:194563
decreased pancreatic beta cell proliferation J:194563
normal homeostasis/metabolism phenotype J:194563
impaired glucose tolerance J:194563
small pancreatic islets J:194563
Hipk3tm1b(EUCOMM)Hmgu/Hipk3tm1b(EUCOMM)Hmgu
C57BL/6N-Hipk3tm1b(EUCOMM)Hmgu/Ieg 		abnormal auditory brainstem response J:211773
decreased heart rate J:211773
decreased locomotor activity J:211773
decreased prepulse inhibition J:211773
decreased startle reflex J:211773
increased circulating alanine transaminase level J:211773
increased fasting circulating glucose level J:211773
increased heart rate variability J:211773
increased mean platelet volume J:211773
prolonged RR interval J:211773
thrombocytosis J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory