Hk2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hk2
hexokinase 2
MGI:1315197

8 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hk2^tm1.1Uku/Hk2^tm1.1Uku B6.129P2-Hk2^tm1.1Uku/Kctt	no abnormal phenotype detected	J:82809
Hk2^tm1.1Uku/Hk2^tm1.1Uku Tg(GFAP-cre)25Mes/0 B6.Cg-Hk2^tm1.1Uku Tg(GFAP-cre)25Mes	abnormal cerebellar granule cell migration	J:210113
	abnormal cerebellum external granule cell layer morphology	J:210113
	abnormal neuronal precursor proliferation	J:210113
	irregular external granule cell layer thickness	J:210113
Hk2^tm1Laak/Hk2⁺ involves: 129P2/OlaHsd * BALB/c * DBA/2	decreased body weight	J:56644
Hk2^tm1Laak/Hk2^tm1Laak involves: 129P2/OlaHsd * BALB/c * DBA/2	embryonic growth retardation	J:56644
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:56644

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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