Slit2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slit2
slit guidance ligand 2
MGI:1315205

13 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ext1^tm1Yama/Ext1⁺ Slit2^tm1Matl/Slit2^tm1Matl Tg(Nes-cre)1Kln/0 involves: 129S2/SvPas * 129S5/SvEvBrd * C57BL/6 * SJL	abnormal axon guidance	J:86465
Gdnf^tm1Rosl/Gdnf⁺ Slit2^tm1Matl/Slit2^tm1Matl involves: 129S2/SvPas	abnormal ureter morphology	J:90324
Ntn1^Gt(ST629)Byg/Ntn1^Gt(ST629)Byg Slit2^tm1Matl/Slit2^tm1Matl involves: 129P2/OlaHsd * 129S2/SvPas	abnormal cell adhesion	J:106011
	abnormal mammary gland duct morphology	J:106011
Robo3^tm1Matl/Robo3^tm1Matl Slit1^tm1.1Matl/Slit1^tm1.1Matl Slit2^tm1Matl/Slit2^tm1Matl involves: 129/Sv * CD-1	abnormal axon guidance	J:89438
Robo3^tm1Matl/Robo3^tm1Matl Slit2^tm1Matl/Slit2^tm1Matl involves: 129/Sv * CD-1	abnormal axon guidance	J:89438
Slit1^tm1.1Matl/Slit1⁺ Slit2^tm1Matl/Slit2^tm1Matl involves: 129S2/SvPas	abnormal olfactory tract morphology	J:119469
Slit1^tm1.1Matl/Slit1^tm1.1Matl Slit2^tm1Matl/Slit2⁺ involves: 129S2/SvPas	abnormal olfactory tract morphology	J:119469
Slit1^tm1.1Matl/Slit1^tm1.1Matl Slit2^tm1Matl/Slit2^tm1Matl involves: 129S2/SvPas	abnormal embryonic/fetal subventricular zone morphology	J:130430
	abnormal neurite morphology	J:130430
	abnormal olfactory lobe morphology	J:119469
	abnormal olfactory tract morphology	J:119469
	normal nervous system phenotype	J:130430
	perinatal lethality, complete penetrance	J:130430
Slit1^tm1.1Matl/Slit1^tm1.1Matl Slit2^tm1Matl/Slit2^tm1Matl Slit3^tm1.1Dor/Slit3⁺ involves: 129S1/Sv * 129S2/SvPas	abnormal axon guidance	J:89780
	abnormal spinal cord lateral column morphology	J:89780
	abnormal spinal cord ventral commissure morphology	J:89780
Slit1^tm1.1Matl/Slit1^tm1.1Matl Slit2^tm1Matl/Slit2^tm1Matl Slit3^tm1.1Dor/Slit3^tm1.1Dor involves: 129S1/Sv * 129S2/SvPas	abnormal axon guidance	J:89780
	abnormal spinal cord lateral column morphology	J:89780
Slit2^tm1Matl/Slit2^tm1Matl Slit3^tm1.1Dor/Slit3^tm1.1Dor involves: 129S1/Sv * 129S2/SvPas	abnormal mammary gland duct morphology	J:141875
	increased mammary gland epithelial cell proliferation	J:141875

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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