Cacng2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cacng2
calcium channel, voltage-dependent, gamma subunit 2
MGI:1316660

47 phenotypes from 8 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cacng2^em1Tern/Cacng2^em1Tern C57BL/6J-Cacng2^em1Tern	abnormal miniature excitatory postsynaptic currents	J:301313
	decreased miniature excitatory postsynaptic current amplitude	J:301313
	decreased miniature excitatory postsynaptic current frequency	J:301313
Cacng2^stg-3J/Cacng2^stg-3J B6C3-Cacng2^stg-3J/J	normal nervous system phenotype	J:96506
Cacng2^stg-wag/Cacng2^stg-wag B6.MRL-Cacng2^stg-wag/J	absence seizures	J:96506
Cacng2^stg/Cacng2^stg B6C3Fe a/a-Cacng2^stg	abnormal brain wave pattern	J:11008, J:15527
	abnormal CNS synapse formation	J:15527
	abnormal hippocampal mossy fiber morphology	J:15527
	abnormal innervation	J:15527
	abnormal neuron differentiation	J:15527
	absence seizures	J:15527
	ataxia	J:11008
	decreased body size	J:11008
	head tossing	J:11008
	impaired swimming	J:11008
	loss of hippocampal neurons	J:15527
	male infertility	J:11008
Cacng2^stg/Cacng2^stg B6C3Fe a/a-Cacng2^stg/J	abnormal brain wave pattern	J:91987
	abnormal CNS synapse formation	J:116541
	abnormal crista ampullaris morphology	J:91987
	abnormal Purkinje cell innervation	J:116541
	abnormal synapse morphology	J:192431
	abnormal synaptic vesicle morphology	J:116541
	abnormal synaptic vesicle number	J:116541
	abnormal thalamus morphology	J:192431
	abnormal type I vestibular cell	J:91987
	abnormal vestibular hair cell morphology	J:91987
	circling	J:91987
	decreased CNS synapse formation	J:116541
	decreased startle reflex	J:91987
	decreased vertical activity	J:91987
	head bobbing	J:91987
	head shaking	J:91987
	head tossing	J:91987
	hyperactivity	J:91987
	impaired coordination	J:91987
	impaired righting response	J:91987
	impaired swimming	J:91987
	increased or absent threshold for auditory brainstem response	J:91987
	stereotypic behavior	J:91987
Cacng2^stg/Cacng2^stg involves: A/J	abnormal miniature excitatory postsynaptic currents	J:163184
	absence of AMPA-mediated synaptic currents	J:163184
	ataxia	J:138791
	decreased body weight	J:138791
Cacng2^stg/Cacng2^stg involves: A/J * C3HeB/FeJ * C57BL/6J	abnormal CNS synaptic transmission	J:106959
	abnormal motor neuron morphology	J:121463
	abnormal neuromuscular synapse morphology	J:121463
	normal nervous system phenotype	J:121463
Cacng2^stg/Cacng2^stg Not Specified	reduced AMPA-mediated synaptic currents	J:140010
Cacng2^tm1.1Mwa/Cacng2^tm1.1Mwa involves: C57BL/6 * C57BL/6N * CBA	abnormal gait	J:163029
	abnormal locomotor coordination	J:163029
	ataxia	J:163029
	decreased body weight	J:163029
	decreased excitatory postsynaptic current amplitude	J:163029
	head bobbing	J:163029
	reduced AMPA-mediated synaptic currents	J:163029
Cacng2^tm1.1Suto/Cacng2^tm1.1Suto Not Specified	abnormal AMPA-mediated synaptic currents	J:163184
	increased miniature excitatory postsynaptic current amplitude	J:163184
	normal nervous system phenotype	J:163184
Cacng2^{tm1b(KOMP)Mbp}/Cacng2^{tm1b(KOMP)Mbp} C57BL/6N-A^tm1Brd Cacng2^{tm1b(KOMP)Mbp}/MbpMmucd	preweaning lethality, incomplete penetrance	J:211773
Cacng2^tm2.1Suto/Cacng2^tm2.1Suto Not Specified	abnormal AMPA-mediated synaptic currents	J:163184
	decreased miniature excitatory postsynaptic current amplitude	J:163184
	normal nervous system phenotype	J:163184

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