Cacng2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cacng2
calcium channel, voltage-dependent, gamma subunit 2
MGI:1316660

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cacng2^em1Tern/Cacng2^em1Tern Gsg1l^tm1.2Tern/Gsg1l^tm1.2Tern C57BL/6J-Cacng2^em1Tern Gsg1l^tm1.2Tern	abnormal miniature excitatory postsynaptic currents	J:301313
	increased excitatory postsynaptic current amplitude	J:301313
	short excitatory postsynaptic current decay time	J:301313
	short excitatory postsynaptic current rise time	J:301313
Cacng2^stg-3J/Cacng2⁺ Cacng4^tm1Frk/Cacng4⁺ involves: B6C3-Cacng2^stg-3J/J * B6.129-Cacng4^tm1Frk/J	absence seizures	J:96506
Cacng2^stg-3J/Cacng2^stg-3J Cacng4^tm1Frk/Cacng4⁺ involves: B6C3-Cacng2^stg-3J/J * B6.129-Cacng4^tm1Frk/J	absence seizures	J:96506
Cacng2^stg-3J/Cacng2^stg-3J Cacng4^tm1Frk/Cacng4^tm1Frk involves: B6C3-Cacng2^stg-3J/J * B6.129-Cacng4^tm1Frk/J	absence seizures	J:96506
	decreased body size	J:96506
Cacng2^stg-wag/Cacng2^stg-wag Cacng4^tm1Frk/Cacng4^tm1Frk involves: B6.MRL-Cacng2^stg-wag/J * B6.129-Cacng4^tm1Frk/J	absence seizures	J:96506
	decreased body size	J:96506
Cacng2^stg/Cacng2^stg Cacng3^tm1Ran/Cacng3^tm1Ran involves: A/J	abnormal CNS synaptic transmission	J:138791
	abnormal excitatory postsynaptic currents	J:138791
	abnormal miniature excitatory postsynaptic currents	J:138791
	ataxia	J:138791
	decreased body weight	J:138791
	postnatal lethality, incomplete penetrance	J:138791
Cacng2^stg/Cacng2^stg Cacng4^tm1Frk/Cacng4^tm1Frk involves: B6C3Fe a/a-Cacng2^stg/J * B6.129-Cacng4^tm1Frk/J	postnatal lethality, incomplete penetrance	J:96506
	prenatal lethality, incomplete penetrance	J:96506
Cacng2^stg/Cacng2^stg Cacng8^tm1.1Suto/Cacng8^tm1.1Suto involves: A/J	postnatal growth retardation	J:179775
	premature death	J:179775
Cacng2^tm1.1Mwa/Cacng2^tm1.1Mwa Cacng7^tm1.1Mwa/Cacng7^tm1.1Mwa involves: C57BL/6 * C57BL/6N * CBA	abnormal gait	J:163029
	abnormal locomotor coordination	J:163029
	ataxia	J:163029
	decreased body weight	J:163029
	decreased excitatory postsynaptic current amplitude	J:163029
	reduced AMPA-mediated synaptic currents	J:163029

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