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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
G0s2
G0/G1 switch gene 2
MGI:1316737
41 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
G0s2tm1(KOMP)Vlcg/G0s2tm1(KOMP)Vlcg
involves: C57BL/6NTac
abnormal fat cell differentiation J:232077
abnormal lactation J:225236
abnormal liver morphology J:209000
abnormal white adipose tissue physiology J:209000
absent gastric milk in neonates J:225236
decreased body weight J:209000, J:232077
decreased brown adipose tissue amount J:209000
decreased circulating alanine transaminase level J:209000
decreased circulating aspartate transaminase level J:209000
decreased circulating insulin level J:209000
decreased epididymal fat pad weight J:232077
decreased gonadal fat pad weight J:209000, J:225236
decreased inguinal fat pad weight J:209000
decreased kidney weight J:209000
decreased liver triglyceride level J:209000
decreased liver weight J:209000
decreased locomotor activity J:225236
decreased omental fat pad weight J:209000
decreased renal fat pad weight J:209000
decreased susceptibility to diet-induced hepatic steatosis J:209000
decreased susceptibility to induced hypothermia J:225236
decreased total body fat amount J:232077
decreased white fat cell size J:232077
enhanced lipolysis J:209000, J:225236
improved glucose tolerance J:209000
increased circulating free fatty acids level J:209000
increased circulating glycerol level J:225236
increased insulin sensitivity J:209000
increased oxygen consumption J:225236
normal liver/biliary system phenotype J:232077
maternal effect J:225236
slow postnatal weight gain J:225236
G0s2tm1Jgte/G0s2tm1Jgte
involves: 129S7/SvEvBrd
abnormal brown adipose tissue thermogenesis J:219653
abnormal white adipose tissue physiology J:219653
decreased abdominal adipose tissue amount J:219653
decreased body fat mass J:219653
decreased body weight J:219653
decreased liver triglyceride level J:219653
decreased liver weight J:219653
decreased respiratory quotient J:219653
decreased susceptibility to diet-induced hepatic steatosis J:219653
decreased susceptibility to diet-induced obesity J:219653
decreased susceptibility to induced hypothermia J:219653
decreased total fat pad weight J:219653
decreased white adipose tissue mass J:219653
decreased white fat cell size J:219653
enhanced lipolysis J:219653
improved glucose tolerance J:219653
increased insulin sensitivity J:219653
increased lean body mass J:219653
increased oxygen consumption J:219653
increased triglyceride lipase activity J:219653

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory