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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ptprt
protein tyrosine phosphatase receptor type T
MGI:1321152
14 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ptprtm1Rgsc/Ptprtm1Rgsc
C57BL/6J-Ptprtm1Rgsc 		abnormal excitatory synapse morphology J:298303
abnormal inhibitory synapse morphology J:298303
abnormal miniature inhibitory postsynaptic currents J:298303
behavioral despair J:298303
decreased gamma-aminobutyric acid level J:298303
decreased glutamine level J:298303
enhanced long-term potentiation J:298303
impaired neuron differentiation J:298303
Ptprttm1Sata/Ptprttm1Sata
B6.129P2-Ptprttm1Sata 		increased colon adenoma incidence J:157542
increased incidence of tumors by chemical induction J:157542
Ptprttm1Sata/Ptprttm1Sata
involves: 129P2/OlaHsd 		normal behavior/neurological phenotype J:298303
behavioral despair J:298303
decreased gamma-aminobutyric acid level J:298303
decreased miniature inhibitory postsynaptic current frequency J:298303
decreased neuronal stem cell self-renewal J:298303
enhanced long-term potentiation J:298303
normal homeostasis/metabolism phenotype J:298303
impaired neuron differentiation J:298303
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory