Trex1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trex1
three prime repair exonuclease 1
MGI:1328317

17 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Arih1^em3Gpt/Arih1^em3Gpt Lyz2^em1(icre)Gpt/Lyz2⁺ Trex1^em1Gpt/Trex1^em1Gpt C57BL/6JGpt-Arih1^em3Gpt Trex1^em1Gpt Lyz2^em1(icre)Gpt	normal growth/size/body region phenotype	J:330879
	normal immune system phenotype	J:330879
	normal mortality/aging	J:330879
Cgas^{tm1a(EUCOMM)Hmgu}/Cgas^{tm1a(EUCOMM)Hmgu} Trex1^tm1Tld/Trex1^tm1Tld involves: 129P2/OlaHsd * C57BL/6N	increased susceptibility to Retroviridae infection	J:234263
Del(1Aim2-Ifi205)1Stsn/+ Trex1^tm1Tld/Trex1^tm1Tld involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N	heart inflammation	J:234263
	increased autoantibody level	J:234263
	increased inflammatory response	J:234263
	kidney inflammation	J:234263
	myositis	J:234263
	premature death	J:234263
	stomach inflammation	J:234263
Del(1Aim2-Ifi205)1Stsn/Del(1Aim2-Ifi205)1Stsn Trex1^tm1Tld/Trex1^tm1Tld involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N	heart inflammation	J:234263
	increased autoantibody level	J:234263
	increased inflammatory response	J:234263
	kidney inflammation	J:234263
	myositis	J:234263
	premature death	J:234263
	stomach inflammation	J:234263
Ighm^tm1Cgn/Ighm^tm1Cgn Trex1^tm1Tld/Trex1^tm1Tld involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	cardiac fibrosis	J:181257
	increased inflammatory response	J:181257
	kidney inflammation	J:181257
	myocarditis	J:181257
	premature death	J:181257
	normal renal/urinary system phenotype	J:181257
	tubular nephritis	J:181257
Mavs^tm1Itl/Mavs^tm1Itl Trex1^tm1Tld/Trex1^tm1Tld involves: 129P2/OlaHsd * C57BL/6	increased inflammatory response	J:181257
	myocarditis	J:181257
	myositis	J:181257
	premature death	J:181257
	skin inflammation	J:181257
	stomach inflammation	J:181257
Rag2^tm1.1Cgn/Rag2^tm1.1Cgn Trex1^tm1Tld/Trex1^tm1Tld involves: 129P2/OlaHsd * C57BL/6	normal immune system phenotype	J:181257
	normal mortality/aging	J:181257
Sting1^tm1Gnb/Sting1^tm1Gnb Trex1^tm1Tld/Trex1^tm1Tld involves: 129P2/OlaHsd * C57BL/6	normal immune system phenotype	J:181257
	normal mortality/aging	J:181257
Tcra^tm1Mom/Tcra^tm1Mom Trex1^tm1Tld/Trex1^tm1Tld involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	colitis	J:181257
	normal immune system phenotype	J:181257
	increased inflammatory response	J:181257
	normal mortality/aging	J:181257
	myositis	J:181257
	skin inflammation	J:181257

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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