Bard1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bard1
BRCA1 associated RING domain 1
MGI:1328361

17 phenotypes from 6 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Bard1^tm1.1Rjbr/Bard1^tm1.1Rjbr involves: 129S6/SvEvTac * C57BL/6J	abnormal DNA replication	J:269011
	arrest of spermatogenesis	J:269011
	decreased male germ cell number	J:269011
	increased cellular sensitivity to DNA damaging agents	J:269011
	male infertility	J:269011
	normal neoplasm	J:269011
	small testis	J:269011
Bard1^tm1Thl/Bard1^tm1Thl involves: 129S1/Sv	abnormal developmental patterning	J:84329
	abnormal embryonic tissue morphology	J:84329
	abnormal gastrulation	J:84329
	embryonic lethality between implantation and somite formation, complete penetrance	J:84329
	inner cell mass degeneration	J:84329
Bard1^tm1Thl/Bard1^tm2Thl Tg(Hsp70-1-cre)1Arge/0 involves: 129/Sv * 129S1/Sv * C57BL/6J * CBA	embryonic lethality, complete penetrance	J:134977
Bard1^tm1Thl/Bard1^tm2Thl Wap^tm1(cre)Arge/0 involves: 129S1/Sv * C57BL/6J	increased mammary adenocarcinoma incidence	J:134977
Bard1^tm2.1Rjbr/Bard1^tm2.1Rjbr involves: 129S6/SvEvTac * C57BL/6J	abnormal DNA replication	J:269011
	arrest of spermatogenesis	J:269011
	decreased male germ cell number	J:269011
	increased cellular sensitivity to DNA damaging agents	J:269011
	male infertility	J:269011
	neoplasm	J:269011
	small testis	J:269011
Bard1^tm2Thl/Bard1^tm2Thl involves: 129 * C57BL/6J	no abnormal phenotype detected	J:134977
Bard1^tm2Thl/Bard1^tm2Thl Wap^tm1(cre)Arge/0 involves: 129/Sv * 129S1/Sv * C57BL/6J	increased mammary adenocarcinoma incidence	J:134977
Bard1^tm3.1Rjbr/Bard1^tm3.1Rjbr involves: 129S6/SvEvTac * C57BL/6J	prenatal lethality, complete penetrance	J:269011
Bard1^tm4.2Rjbr/Bard1^tm4.2Rjbr involves: 129S6/SvEvTac * C57BL/6J	prenatal lethality, complete penetrance	J:269011

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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