Smarcb1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Smarcb1
SWI/SNF related BAF chromatin remodeling complex subunit B1
MGI:1328366

33 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ccnd1^tm1Wbg/Ccnd1^tm1Wbg Smarcb1^tm1Gvk/Smarcb1⁺ involves: 129/Sv * 129S2/SvPas * C57BL/6J * SJL/J	abnormal eye development	J:101185
	abnormal nervous system development	J:101185
	decreased body size	J:101185
	decreased tumor incidence	J:101185
Smarcb1^tm1Sho/Smarcb1⁺ Tg(LPV-TAg121)2Tvd/0 involves: 129S6/SvEvTac * C57BL/6J * DBA/2J	increased carcinoma incidence	J:120820
	increased malignant tumor incidence	J:120820
Smarcb1^tm2Sho/Smarcb1⁺ Trp53^tm1Brn/Trp53⁺ Tg(GFAP-cre)#Gtm/0 involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA	excessive scratching	J:226786
Smarcb1^tm2Sho/Smarcb1⁺ Trp53^tm1Brn/Trp53^tm1Brn Tg(GFAP-cre)#Gtm/0 involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA	excessive scratching	J:226786
Smarcb1^tm2Sho/Smarcb1^tm2Sho Trp53^tm1Brn/Trp53⁺ Tg(GFAP-cre)#Gtm/0 involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA	abnormal brain white matter morphology	J:226786
	normal neoplasm	J:226786
Smarcb1^tm2Sho/Smarcb1^tm2Sho Trp53^tm1Brn/Trp53^tm1Brn Tg(GFAP-cre)#Gtm/0 involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA	abnormal brain white matter morphology	J:226786
	abnormal cerebellar granule cell migration	J:226786
	abnormal cerebellar layer morphology	J:226786
	abnormal cerebellum external granule cell layer morphology	J:226786
	abnormal cerebellum morphology	J:226786
	abnormal cerebral cortex morphology	J:226786
	abnormal corpus callosum morphology	J:226786
	abnormal gait	J:226786
	abnormal hippocampus morphology	J:226786
	abnormal limb posture	J:226786
	abnormal locomotor behavior	J:226786
	abnormal stride length	J:226786
	ataxia	J:226786
	circling	J:226786
	decreased body size	J:226786
	decreased body weight	J:226786
	decreased oligodendrocyte number	J:226786
	decreased survivor rate	J:226786
	dystonia	J:226786
	excessive scratching	J:226786
	gliosis	J:226786
	hindlimb paralysis	J:226786
	impaired coordination	J:226786
	increased brain tumor incidence	J:226786
	lethargy	J:226786
	seizures	J:226786
	tremors	J:226786

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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