Msh5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Msh5
mutS homolog 5
MGI:1329021

25 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Msh5^em1Jzc/Msh5^em1Jzc involves: C57BL/6	abnormal ovarian follicle morphology	J:241778
	absent oocytes	J:241778
	female infertility	J:241778
	ovary atrophy	J:241778
Msh5^{tm1b(EUCOMM)Wtsi}/Msh5^{tm1b(EUCOMM)Wtsi} C57BL/6N-Msh5^{tm1b(EUCOMM)Wtsi}/Ieg	abnormal lens morphology	J:211773
	decreased bone mineral density	J:211773
	increased circulating unsaturated transferrin level	J:211773
	increased leukocyte cell number	J:211773
	increased startle reflex	J:211773
Msh5^tm1Htr/Msh5^tm1Htr involves: 129P2/OlaHsd * FVB	abnormal female meiosis	J:53516
	abnormal synaptonemal complex	J:180025
	absent oocytes	J:53516
	absent ovarian follicles	J:53516
	arrest of male meiosis	J:53516
	azoospermia	J:53516
	decreased testis weight	J:53516
	female infertility	J:53516
	increased granulosa cell tumor incidence	J:180025
	increased male germ cell apoptosis	J:53516
	male infertility	J:53516
	small ovary	J:53516
Msh5^tm1Rak/Msh5^tm1Rak involves: 129/Sv * C57BL/6J * SJL	abnormal female meiosis	J:51921
	abnormal male meiosis	J:51921, J:62204
	abnormal ovarian bursa morphology	J:51921
	azoospermia	J:51921
	decreased oocyte number	J:51921
	female infertility	J:51921
	male infertility	J:51921
	ovary cyst	J:51921
	ovary degeneration	J:51921
	small testis	J:51921

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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