Tulp3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tulp3
TUB like protein 3
MGI:1329045

64 phenotypes from 5 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tulp3^hhkr/Tulp3⁺ involves: C3H/HeH * C57BL/6	abnormal head morphology	J:147584
Tulp3^hhkr/Tulp3^hhkr involves: C3H/HeH * C57BL/6	abnormal caudal neuropore morphology	J:147584
	abnormal digit morphology	J:147584
	abnormal nervous system development	J:147584
	abnormal neural tube morphology	J:147584
	abnormal vertebrae development	J:147584
	clinodactyly	J:147584
	decreased embryonic neuroepithelium thickness	J:147584
	edema	J:147584
	exencephaly	J:147584
	incomplete caudal neuropore closure	J:147584
	incomplete rostral neuropore closure	J:147584
	polydactyly	J:147584
	rib bifurcation	J:147584
	spina bifida cystica	J:147584
	spina bifida occulta	J:147584
Tulp3^hhkr/Tulp3^tm1Jng involves: 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL/6	abnormal eye development	J:147584
	edema	J:147584
	exencephaly	J:147584
	spina bifida	J:147584
Tulp3^m1Kflj/Tulp3^m1Kflj involves: C57BL/6J * FVB/NJ	abnormal skeleton morphology	J:284006
	cleft palate	J:284006
	enlarged kidney	J:284006
	increased blood urea nitrogen level	J:284006
	increased circulating creatinine level	J:284006
	increased kidney cell proliferation	J:284006
	increased rib number	J:284006
	perinatal lethality, incomplete penetrance	J:284006
	polycystic kidney	J:284006
	postnatal lethality	J:284006
Tulp3^m1Kflj/Tulp3^{tm1b(EUCOMM)Hmgu} involves: C57BL/6 * C57BL/6J * C57BL/6N * FVB/NJ	kidney cyst	J:284006
Tulp3^{tm1b(EUCOMM)Hmgu}/Tulp3⁺ C57BL/6N-Tulp3^{tm1b(EUCOMM)Hmgu}/H	decreased fasting circulating glucose level	J:211773
	decreased lean body mass	J:211773
	decreased prepulse inhibition	J:211773
	impaired glucose tolerance	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased circulating bilirubin level	J:211773
	increased total body fat amount	J:211773
Tulp3^{tm1b(EUCOMM)Hmgu}/Tulp3^{tm1b(EUCOMM)Hmgu} C57BL/6N-Tulp3^{tm1b(EUCOMM)Hmgu}/H	preweaning lethality, complete penetrance	J:211773
Tulp3^{tm1b(EUCOMM)Hmgu}/Tulp3^{tm1b(EUCOMM)Hmgu} involves: C57BL/6 * C57BL/6N * FVB/NJ	abnormal craniofacial morphology	J:284006
	abnormal skeleton development	J:284006
	edema	J:284006
	open neural tube	J:284006
	polydactyly	J:284006
	prenatal lethality prior to heart atrial septation	J:284006
Tulp3^{tm1c(EUCOMM)Hmgu}/Tulp3^{tm1c(EUCOMM)Hmgu} Tg(Pax8-rtTA2SM2)1Koes/0 Tg(tetO-cre)1Jaw/0 involves: 129 C57BL/6 * C57BL/6N * DBA * SJL	dilated renal tubule	J:284006
	kidney cyst	J:284006
Tulp3^tm1Jng/Tulp3⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal brain development	J:70060
	abnormal brain morphology	J:70060
	abnormal forebrain morphology	J:70060
	abnormal hindbrain morphology	J:70060
	abnormal midbrain morphology	J:70060
	embryonic lethality, incomplete penetrance	J:70060
	forebrain hypoplasia	J:70060
	hemorrhage	J:70060
	increased embryonic neuroepithelium apoptosis	J:70060
	open neural tube	J:70060
Tulp3^tm1Jng/Tulp3^tm1Jng involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal craniofacial development	J:70060
	abnormal dorsal root ganglion morphology	J:70060
	abnormal hindbrain development	J:70060
	abnormal hindbrain morphology	J:70060
	abnormal midbrain morphology	J:70060
	abnormal neural tube morphology	J:70060
	abnormal neuron specification	J:70060
	abnormal vertebrae morphology	J:70060
	anemia	J:70060
	exencephaly	J:70060
	facial cleft	J:70060
	increased apoptosis	J:70060
	increased embryonic neuroepithelium apoptosis	J:70060
	internal hemorrhage	J:70060
	intracranial hemorrhage	J:70060
	lethality throughout fetal growth and development, complete penetrance	J:70060
	open neural tube	J:70060
	pallor	J:70060
	spina bifida	J:70060

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