S100a4 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

S100a4
S100 calcium binding protein A4
MGI:1330282

11 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
S100a4^tm1.1Abres/S100a4^tm1.1Abres B6.Cg-S100a4^tm1.1Abres	abnormal eosinophil physiology	J:182865
S100a4^tm1.1Abres/S100a4^tm1.1Abres B6.Cg-S100a4^tm1.1Abres	impaired macrophage chemotaxis	J:182865
S100a4^tm1Amba/S100a4^tm1Amba involves: 129S1/Sv * 129X1/SvJ * NMRI	increased fibrosarcoma incidence	J:89563
	increased hepatocellular carcinoma incidence	J:89563
	increased lung carcinoma incidence	J:89563
	increased lymphoma incidence	J:89563
	increased mammary adenocarcinoma incidence	J:89563
	increased tumor incidence	J:89563
	prenatal lethality, incomplete penetrance	J:89563
S100a4^tm1Amba/S100a4^tm1Amba involves: A/Sn	abnormal apoptosis	J:89563
S100a4^tm1Egn/S100a4^tm1Egn involves: 129S6/SvEvTac * BALB/c	no abnormal phenotype detected	J:83971

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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