Magoh Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Magoh
mago homolog, exon junction complex core component
MGI:1330312

21 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Emx1^tm1(cre)Krj/Emx1⁺ Magoh^{tm1c(KOMP)Dlsi}/Magoh⁺ involves: 129S2/SvPas * C57BL/6J	microcephaly	J:235650
Magoh^{Gt(AG0150)Wtsi}/Magoh⁺ involves: 129P2/OlaHsd	decreased body weight	J:159625
	decreased brain size	J:159625
	decreased survivor rate	J:159625
	hypopigmentation	J:159625
	postnatal lethality, incomplete penetrance	J:159625
Magoh^{Gt(AT0027)Wtsi}/Magoh⁺ involves: 129P2/OlaHsd	decreased body weight	J:159625
	decreased brain size	J:159625
	decreased survivor rate	J:159625
	hypopigmentation	J:159625
	postnatal lethality, incomplete penetrance	J:159625
Magoh^Mos2/Magoh⁺ involves: BALB/cJ * C57BL/6	thin cerebral cortex	J:213515
Magoh^Mos2/Magoh⁺ involves: BALB/cJ * C57BL/6J	abnormal brain development	J:159625
	abnormal mitotic spindle morphology	J:159625
	abnormal neuron apoptosis	J:159625
	abnormal neuron proliferation	J:159625
	decreased body weight	J:159625
	decreased brain size	J:159625, J:240595
	decreased forebrain size	J:240595
	decreased neocortex size	J:240595
	decreased neuron number	J:159625
	decreased survivor rate	J:159625
	ectopic cortical neuron	J:240595
	embryonic growth retardation	J:240595
	hypopigmentation	J:159625
	increased brain apoptosis	J:240595
	postnatal lethality, incomplete penetrance	J:159625
Magoh^Mos2/Magoh^Mos2 involves: BALB/cJ * C57BL/6J	embryonic lethality during organogenesis, complete penetrance	J:159625
Magoh^{tm1c(KOMP)Dlsi}/Magoh⁺ Emx1^tm1(cre)Krj/Emx1⁺ B6.Cg-Magoh^{tm1c(KOMP)Dlsi} Emx1^tm1(cre)Krj	decreased brain size	J:213515
	thin cerebral cortex	J:213515
Magoh^{tm1c(KOMP)Dlsi}/Magoh^{tm1c(KOMP)Dlsi} B6J(C3)-Magoh^{tm1c(KOMP)Dlsi}	no abnormal phenotype detected	J:213515
Magoh^{tm1d(KOMP)Dlsi}/Magoh⁺ involves: C57BL/6J * FVB	belly spot	J:213515
	decreased brain size	J:213515
	hypopigmentation	J:213515
	normal mortality/aging	J:213515
	thin cerebral cortex	J:213515

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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