Acox1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
MGI:1330812

27 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Acox1^em1Wum/Acox1^em1Wum Tg(Adipoq-cre)1Evdr/0 involves: FVB/NJ	normal adipose tissue phenotype	J:270463
	normal growth/size/body region phenotype	J:270463
	normal homeostasis/metabolism phenotype	J:270463
Acox1^lampe1/Acox1^lampe1 involves: C57BL/6J	abnormal hepatocyte morphology	J:174942
	abnormal liver morphology	J:174942
	enlarged liver	J:174942
	increased circulating alanine transaminase level	J:174942
	increased circulating alkaline phosphatase level	J:174942
	increased hepatocellular carcinoma incidence	J:174942
	liver inflammation	J:174942
	microvesicular hepatic steatosis	J:174942
	postnatal growth retardation	J:174942
	reduced fertility	J:174942
Acox1^tm1Jkr/Acox1⁺ involves: 129P2/OlaHsd * C57BL/6J	microvesicular hepatic steatosis	J:35794
Acox1^tm1Jkr/Acox1^tm1Jkr involves: 129P2/OlaHsd * C57BL/6J	abnormal liver physiology	J:35794
	abnormal liver regeneration	J:48180
	abnormal spermatid morphology	J:35794
	abnormal spermatogenesis	J:35794
	decreased body weight	J:35794
	decreased Leydig cell number	J:35794
	female infertility	J:35794
	hyperlipidemia	J:35794
	increased hepatocellular carcinoma incidence	J:35794
	increased hepatoma incidence	J:48180
	increased liver weight	J:35794
	male infertility	J:35794
	microvesicular hepatic steatosis	J:48180
	pale liver	J:35794
	small ovary	J:35794
	small testis	J:35794

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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