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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Csrp3
cysteine and glycine-rich protein 3
MGI:1330824
37 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Csrp3tm1.1Kage/Csrp3tm1.1Kage
involves: C57BL/6 * C57BL/6J * C57BL/6N * SJL 		abnormal cardiac muscle relaxation J:307893
decreased heart left ventricle muscle contractility J:307893
normal embryo phenotype J:307893
increased heart left ventricle size J:307893
increased heart left ventricle weight J:307893
increased heart weight J:307893
normal mortality/aging J:307893
normal reproductive system phenotype J:307893
Csrp3tm1.1Rkn/Csrp3+
either: (involves: Black Swiss) or (involves: C57BL/6N) 		abnormal heart morphology J:170878
abnormal heart septum morphology J:170878
cardiomyopathy J:170878
increased cardiac muscle contractility J:170878
premature death J:170878
Csrp3tm1.1Rkn/Csrp3tm1.1Rkn
either: (involves: Black Swiss) or (involves: C57BL/6N) 		abnormal heart morphology J:170878
abnormal heart septum morphology J:170878
abnormal heart ventricle morphology J:170878
abnormal skeletal muscle fiber morphology J:170878
cardiac fibrosis J:170878
cardiomyopathy J:170878
decreased body weight J:170878
decreased response of heart to induced stress J:170878
increased cardiac muscle contractility J:170878
increased heart left ventricle weight J:170878
increased heart weight J:170878
increased lung weight J:170878
increased variability of skeletal muscle fiber size J:170878
myocardial fiber disarray J:170878
myopathy J:170878
premature death J:170878
Csrp3tm1Crni/Csrp3tm1Crni
Not Specified 		abnormal actin cytoskeleton morphology J:38213
abnormal cardiovascular system physiology J:66250
abnormal heart echocardiography feature J:66250
abnormal intercalated disk morphology J:138969
abnormal myocardial fiber physiology J:66250
cardiac hypertrophy J:38213
cardiac interstitial fibrosis J:38213
congestive heart failure J:66250
decreased cardiac muscle contractility J:66250, J:88510
decreased heart ventricle muscle contractility J:38213
dilated cardiomyopathy J:38213, J:66250, J:88510
dilated heart left ventricle J:38213, J:66250, J:88510
enlarged heart J:38213
increased heart weight J:38213
increased myocardial fiber size J:138969
postnatal lethality, incomplete penetrance J:38213
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory