Lin7c Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lin7c
lin-7 homolog C, crumbs cell polarity complex component
MGI:1330839

16 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lin7c^tm1Dsb/Lin7c^tm1Dsb involves: 129S1/Sv * 129X1/SvJ	abnormal kidney morphology	J:134806
	abnormal kidney physiology	J:134806
	abnormal renal tubule epithelium morphology	J:134806
	decreased body weight	J:134806
	decreased creatinine clearance	J:134806
	decreased kidney weight	J:134806
	decreased urine osmolality	J:134806
	dilated renal tubule	J:134806
	increased blood urea nitrogen level	J:134806
	increased kidney apoptosis	J:134806
	increased urine sodium level	J:134806
	polycystic kidney	J:134806
	polyuria	J:134806
	renal interstitial fibrosis	J:134806
	single kidney	J:134806
Lin7c^tm2Dsb/Lin7c^tm2Dsb Tg(Hoxb7-cre)13Amc/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:134806
Lin7c^tm2Dsb/Lin7c^tm2Dsb Tg(Pax3-cre)1Joe/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	decreased kidney weight	J:134806
	dilated renal tubule	J:134806
	increased kidney apoptosis	J:134806
	renal interstitial fibrosis	J:134806

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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