Ugcg Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ugcg
UDP-glucose ceramide glucosyltransferase
MGI:1332243

28 phenotypes from 6 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ugcg^em1(IMPC)H/Ugcg⁺ C57BL/6NTac-Ugcg^em1(IMPC)H/H	decreased lymphocyte cell number	J:211773
	increased circulating alanine transaminase level	J:211773
	increased neutrophil cell number	J:211773
Ugcg^em1(IMPC)H/Ugcg^em1(IMPC)H C57BL/6NTac-Ugcg^em1(IMPC)H/H	preweaning lethality, complete penetrance	J:211773
Ugcg^tm1Hjg/Ugcg^tm1.1Hjg Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	abnormal axon morphology	J:101155
	abnormal gait	J:101155
	abnormal lipid homeostasis	J:101155
	abnormal myelination	J:101155
	abnormal Purkinje cell morphology	J:101155
	ataxia	J:101155
	decreased body weight	J:101155
	impaired balance	J:101155
	impaired righting response	J:101155
	limb grasping	J:101155
	postnatal lethality, complete penetrance	J:101155
Ugcg^tm1Hjg/Ugcg^tm1Hjg Pax8^{tm1.1(cre)Mbu}/Pax8⁺ involves: 129P2/OlaHsd * C57BL/6	decreased urine pH	J:197393
	normal mortality/aging	J:197393
	normal renal/urinary system phenotype	J:197393
Ugcg^tm1Rlp/Ugcg^tm1Rlp involves: 129S6/SvEvTac	abnormal extraembryonic tissue morphology	J:76736, J:80111
	abnormal Reichert's membrane morphology	J:76736
	decreased embryo size	J:76736, J:80111
	disorganized extraembryonic tissue	J:76736
	embryonic lethality between implantation and placentation, complete penetrance	J:76736, J:80111
	increased ectoderm apoptosis	J:76736, J:80111
Ugcg^tm1Rlp/Ugcg^tm2Rlp involves: 129S6/SvEvTac	abnormal ectoderm development	J:76736
Ugcg^tm1Rlp/Ugcg^tm2Rlp involves: 129S6/SvEvTac	abnormal plasma membrane morphology	J:76736
Ugcg^tm1Rlp/Ugcg^tm4Rlp Tg(Nes-cre)1Kln/0 involves: 129S6/SvEvTac * C57BL/6 * SJL	abnormal gait	J:103415
	limb grasping	J:103415
	Purkinje cell degeneration	J:103415
Ugcg^tm4Rlp/Ugcg^tm4Rlp involves: 129S6/SvEvTac * C57BL/6	no abnormal phenotype detected	J:103415
Ugcg^tm4Rlp/Ugcg^tm4Rlp Tg(Nes-cre)1Kln/0 involves: 129S6/SvEvTac * C57BL/6 * SJL	abnormal gait	J:103415
	limb grasping	J:103415
	Purkinje cell degeneration	J:103415

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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