Mrpl22 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mrpl22
mitochondrial ribosomal protein L22
MGI:1333794

23 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mrpl22^{tm1b(KOMP)Mbp}/Mrpl22⁺ C57BL/6N-Mrpl22^{tm1b(KOMP)Mbp}/J	impaired pupillary reflex	J:211773
	increased fasting circulating glucose level	J:211773
Mrpl22^{tm1b(KOMP)Mbp}/Mrpl22^{tm1b(KOMP)Mbp} C57BL/6N-A^tm1Brd Mrpl22^{tm1b(KOMP)Mbp}/JMmucd	abnormal cell cycle checkpoint function	J:290315
	abnormal embryonic epiblast morphology	J:290315
	abnormal mitochondrial ATP synthesis coupled electron transport	J:290315
	abnormal mitochondrial crista morphology	J:290315
	abnormal mitochondrial morphology	J:290315
	abnormal mitochondrial physiology	J:290315
	abnormal respiratory electron transport chain	J:290315
	absent allantois	J:290315
	absent head fold	J:279207, J:290315
	absent primitive node	J:279207, J:290315
	normal cellular phenotype	J:290315
	decreased cellular ATP level	J:290315
	decreased egg cylinder size	J:279207
	decreased embryo size	J:279207, J:290315
	embryonic growth arrest	J:279207, J:290315
	embryonic growth retardation	J:290315
	embryonic lethality between implantation and placentation, complete penetrance	J:279207, J:290315
	failure of primitive streak formation	J:279207, J:290315
	failure to gastrulate	J:279207, J:290315
Mrpl22^{tm1b(KOMP)Mbp}/Mrpl22^{tm1b(KOMP)Mbp} C57BL/6N-Mrpl22^{tm1b(KOMP)Mbp}/J	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24