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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mbd3
methyl-CpG binding domain protein 3
MGI:1333812
5 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Mbd3tm1Bh/Mbd3tm1Bh
involves: 129P2/OlaHsd * C57BL/6 		embryonic lethality between implantation and somite formation, complete penetrance J:68356
Mbd3tm2Bh/Mbd3tm2Bh
Tg(Vil1-cre)20Syr/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 		abnormal small intestinal crypt cell proliferation J:167984
increased incidence of tumors by chemical induction J:167984
increased susceptibility to induced colitis J:167984
increased tumor growth/size J:167984
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory