Mbd2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mbd2
methyl-CpG binding domain protein 2
MGI:1333813

16 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mbd2^tm1Bh/Mbd2^tm1Bh involves: 129P2/OlaHsd * C57BL/6	abnormal maternal nurturing	J:68356
	abnormal pup retrieval	J:68356
	decreased litter size	J:68356
Mbd2^tm1Bh/Mbd2^tm1Bh NOD.129P2(B6)-Mbd2^tm1Bh	abnormal CD4-positive, alpha-beta T cell physiology	J:323838
	abnormal CD8-positive, alpha-beta cytotoxic T cell morphology	J:323838
	abnormal effector T cell morphology	J:323838
	abnormal homeostasis	J:323838
	abnormal pancreatic islet morphology	J:323838
	enlarged lymph nodes	J:323838
	enlarged spleen	J:323838
	hyperglycemia	J:323838
	increased T cell proliferation	J:323838
	increased T-helper 1 cell number	J:323838
	increased T-helper 2 cell number	J:323838
	insulitis	J:323838
	salivary gland inflammation	J:323838

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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