Grap2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Grap2
GRB2-related adaptor protein 2
MGI:1333842

10 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Grap2^tm1Amch/Grap2^tm1Amch involves: 129S1/Sv * 129X1/SvJ	arrested T cell differentiation	J:76696
	decreased CD4-positive, alpha-beta T cell number	J:76696
	decreased CD8-positive, alpha-beta T cell number	J:76696
	decreased thymocyte number	J:76696
	increased double-negative T cell number	J:76696
Grap2^tm1Eac/Grap2^tm1Eac involves: C57BL/6	abnormal CD4-positive, alpha beta T cell morphology	J:92023
	abnormal double-negative T cell morphology	J:92023
	decreased T cell number	J:92023
	decreased thymocyte number	J:92023
	increased activated T cell number	J:92023
	increased memory T cell number	J:92023

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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