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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gab2
growth factor receptor bound protein 2-associated protein 2
MGI:1333854
19 phenotypes from 6 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gab2em1(IMPC)Bay/Gab2em1(IMPC)Bay
C57BL/6N-Gab2em1(IMPC)Bay/BayMmucd 		short tibia J:211773
Gab2tm1Gsf/Gab2tm1Gsf
involves: BALB/c 		abnormal response to infection J:122213
decreased susceptibility to Retroviridae infection J:122429
Gab2tm1Hhg/Gab2tm1Hhg
involves: 129S4/SvJae 		decreased mast cell degranulation J:70424
decreased mast cell number J:70424
decreased susceptibility to type I hypersensitivity reaction J:70424
normal immune system phenotype J:70424
Gab2tm1Pngr/Gab2tm1Pngr
B6.Cg-Gab2tm1Pngr 		abnormal osteoclast differentiation J:97515
abnormal osteoclast morphology J:97515
decreased bone marrow cell number J:97515
decreased bone resorption J:97515
decreased osteoclast cell number J:97515
increased bone mass J:97515
increased compact bone mass J:97515
increased trabecular bone mass J:97515
osteopetrosis J:97515
Gab2tm1Thir/Gab2tm1Thir
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal mast cell differentiation J:75092
abnormal mast cell physiology J:75092
decreased mast cell number J:75092
normal hematopoietic system phenotype J:75092
Gab2tm4.1Thir/Gab2tm4.1Thir
involves: 129T/SvJcl * C57BL/6Jcl 		decreased mast cell degranulation J:178045
decreased mast cell number J:178045
decreased susceptibility to type I hypersensitivity reaction J:178045
normal immune system phenotype J:178045
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory