Gab2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gab2
growth factor receptor bound protein 2-associated protein 2
MGI:1333854

15 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Gab1^tm1Nmoc/Gab1^tm1Nmoc Gab2^tm1Thir/Gab2^tm1Thir Tg(Myh6-cre)2182Mds/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N	abnormal cardiac muscle relaxation	J:124033
	abnormal endocardium morphology	J:124033
	abnormal heart left ventricle morphology	J:124033
	abnormal heart morphology	J:124033
	congestive heart failure	J:124033
	decreased cardiac muscle contractility	J:124033
	dilated heart	J:124033
	increased heart weight	J:124033
	increased left ventricle diastolic pressure	J:124033
	premature death	J:124033
	thin interventricular septum	J:124033
Gab2^tm2.1Thir/Gab2^tm2.1Thir involves: 129T/SvJcl * C57BL/6Jcl	normal immune system phenotype	J:178045
Gab2^tm3.1Thir/Gab2^tm3.1Thir involves: 129T/SvJcl * C57BL/6Jcl	decreased mast cell degranulation	J:178045
	decreased mast cell number	J:178045
	decreased susceptibility to type I hypersensitivity reaction	J:178045
	normal immune system phenotype	J:178045

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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