Xirp1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Xirp1
xin actin-binding repeat containing 1
MGI:1333878

28 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Xirp1^tm1Dofr/Xirp1^tm1Dofr involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cardiac muscle contractility	J:159352
	abnormal cardiovascular system morphology	J:159352
	abnormal cardiovascular system physiology	J:159352
	abnormal myocardium layer morphology	J:159352
	abnormal sarcomere morphology	J:159352
	cardiac fibrosis	J:159352
	normal cardiovascular system phenotype	J:159352
	decreased body weight	J:159352
	decreased cardiac muscle contractility	J:159352
	shortened HV interval	J:159352
	shortened QRS complex duration	J:159352
Xirp1^tm1Jl/Xirp1⁺ involves: 129	abnormal trabecula carnea morphology	J:132079
	abnormal ventricle myocardium morphology	J:132079
	cardiac hypertrophy	J:132079
	cardiac interstitial fibrosis	J:132079
	cardiomyopathy	J:132079
	enlarged heart	J:132079
	increased myocardial fiber size	J:132079
Xirp1^tm1Jl/Xirp1^tm1Jl involves: 129	abnormal A band morphology	J:132079
	abnormal I band morphology	J:132079
	abnormal intercalated disk morphology	J:112201, J:132079
	abnormal myocardial fiber calcium currents	J:132079
	abnormal myocardial fiber currents	J:132079
	abnormal myocardial fiber morphology	J:112201, J:132079
	abnormal myocardial fiber sodium currents	J:132079
	abnormal sarcomere morphology	J:132079
	abnormal trabecula carnea morphology	J:132079
	abnormal ventricle myocardium morphology	J:132079
	cardiac hypertrophy	J:112201, J:132079
	cardiac interstitial fibrosis	J:132079
	cardiomyopathy	J:132079
	diffuse Z line	J:132079
	enlarged heart	J:132079
	increased myocardial fiber size	J:132079
	prolonged P wave	J:132079
	prolonged QT interval	J:132079

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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