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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Aspm
abnormal spindle microtubule assembly
MGI:1334448
32 phenotypes from 6 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Aspmem1Mama/Aspmem1Mama
involves: C57BL/6 * C57BL/6J * CBA 		abnormal male germ cell physiology J:310617
abnormal neocortex morphology J:310617
normal cellular phenotype J:310617
decreased brain weight J:310617
AspmGt(AA0137)Wtsi/AspmGt(AA0137)Wtsi
involves: 129P2/OlaHsd * C57BL/6JOlaHsd 		abnormal neocortex morphology J:164424
asthenozoospermia J:164424
decreased body weight J:164424
decreased brain size J:164424
decreased brain weight J:164424
decreased ovary weight J:164424
decreased testis weight J:164424
microcephaly J:164424
oligozoospermia J:164424
reduced female fertility J:164424
reduced male fertility J:164424
small sperm head J:164424
AspmGt(AJ0069)Wtsi/AspmGt(AJ0069)Wtsi
involves: 129P2/OlaHsd * C57BL/6JOlaHsd 		abnormal neocortex morphology J:164424
asthenozoospermia J:164424
decreased brain weight J:164424
decreased ovary weight J:164424
decreased testis weight J:164424
microcephaly J:164424
oligozoospermia J:164424
reduced female fertility J:164424
reduced male fertility J:164424
small sperm head J:164424
Aspmtm1(cre)Mrc/Aspmtm1(cre)Mrc
Not Specified 		abnormal astrocyte morphology J:228026
abnormal brain development J:228026
abnormal cell cycle J:228026
decreased brain weight J:228026
decreased neuronal precursor cell number J:228026
microcephaly J:228026
thin cerebral cortex J:228026
Aspmtm1.2Kxi/Aspmtm1.2Kxi
involves: C57BL * C57BL/6J * DBA 		abnormal barrel cortex morphology J:205524
abnormal cerebral hemisphere morphology J:205524
abnormal Sertoli cell morphology J:205524
decreased brain weight J:205524
enlarged lateral ventricles J:205524
increased Leydig cell number J:205524
oligozoospermia J:205524
seminiferous tubule degeneration J:205524
small testis J:205524
thin cerebral cortex J:205524
Aspmtm1a(KOMP)Wtsi/Aspmtm1a(KOMP)Wtsi
C57BL/6N-Aspmtm1a(KOMP)Wtsi/Wtsi 		decreased lean body mass J:211773
increased circulating cholesterol level J:211773
increased circulating glycerol level J:211773
increased circulating HDL cholesterol level J:211773
increased total body fat amount J:211773
thrombocytopenia J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory