Lss Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lss
lanosterol synthase
MGI:1336155

12 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lss^em1Zhaol/Lss^em1Zhaol C57BL/6J-Lss^em1Zhaol	abnormal lens development	J:316796
	abnormal lens fiber morphology	J:316796
	developmental cataract	J:316796
	disorganized secondary lens fibers	J:316796
	neonatal lethality, complete penetrance	J:316796
	small lens	J:316796
Lss^{tm1b(KOMP)Wtsi}/Lss⁺ C57BL/6N-Lss^{tm1b(KOMP)Wtsi}/Ieg	abnormal lens morphology	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased leukocyte cell number	J:211773
Lss^{tm1b(KOMP)Wtsi}/Lss^{tm1b(KOMP)Wtsi} C57BL/6N-Lss^{tm1b(KOMP)Wtsi}/Bay	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Lss^{tm1b(KOMP)Wtsi}/Lss^{tm1b(KOMP)Wtsi} C57BL/6N-Lss^{tm1b(KOMP)Wtsi}/Ieg	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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