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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Kcnq3
potassium voltage-gated channel, subfamily Q, member 3
MGI:1336181
17 phenotypes from 4 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Emx1tm1(cre)Krj/?
Kcnq3tm1.1Avtz/Kcnq3tm1.1Avtz
involves: 129S2/SvPas * C57BL/6 		abnormal hippocampus morphology J:208109
abnormal nervous system electrophysiology J:208109
Kcnq3em1(IMPC)H/Kcnq3em1(IMPC)H
C57BL/6N-Kcnq3em1(IMPC)H/H 		abnormal snout morphology J:211773
hyperactivity J:211773
increased blood urea nitrogen level J:211773
increased exploration in new environment J:211773
Kcnq3tm1.1Naas/Kcnq3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal seizure response to electrical stimulation J:154582
Kcnq3tm1.1Naas/Kcnq3+
involves: 129S1/Sv * 129X1/SvJ * FVB/N 		abnormal seizure response to electrical stimulation J:154582
Kcnq3tm1.1Naas/Kcnq3tm1.1Naas
B6.129-Kcnq3tm1.1Naas 		decreased body size J:154582
prenatal lethality, incomplete penetrance J:154582
seizures J:154582
Kcnq3tm1.1Naas/Kcnq3tm1.1Naas
FVB.129-Kcnq3tm1.1Naas 		abnormal hippocampus morphology J:154582
astrocytosis J:154582
decreased body size J:154582
neonatal lethality, incomplete penetrance J:154582
normal nervous system phenotype J:154582
premature death J:154582
seizures J:154582
Kcnq3tm1.1Naas/Kcnq3tm1.1Naas
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal neuron physiology J:154582
prenatal lethality, incomplete penetrance J:154582
seizures J:154582
Kcnq3tm1.1Naas/Kcnq3tm1.1Naas
involves: 129S1/Sv * 129X1/SvJ * FVB/N 		abnormal neuron physiology J:154582
prenatal lethality, incomplete penetrance J:154582
Kcnq3tm1Dgen/Kcnq3tm1Dgen
Not Specified 		abnormal afterhyperpolarization J:142688
abnormal physiological response to xenobiotic J:142688
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory