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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tsix
X (inactive)-specific transcript, opposite strand
MGI:1336196
25 phenotypes from 5 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tsix/Xisttm3Sado/Tsix+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ 		abnormal DNA methylation J:130425
abnormal embryo development J:130425
preweaning lethality, incomplete penetrance J:130425
Tsixtm1Enl/?
involves: 129S4/SvJae 		abnormal allantois morphology J:68136
abnormal chorion morphology J:68136
abnormal developmental patterning J:68136
abnormal ectoplacental cavity morphology J:68136
abnormal ectoplacental cone morphology J:68136
abnormal extraembryonic coelom morphology J:68136
abnormal gastrulation J:68136
abnormal germ layer development J:68136
abnormal mesoderm development J:68136
abnormal visceral yolk sac morphology J:68136
absent egg cylinders J:68136
prenatal lethality, incomplete penetrance J:68136
small amniotic cavity J:68136
Tsixtm1Enl/Tsix+
involves: 129S4/SvJae 		abnormal digestive system physiology J:68136
Tsixtm1Jtl/Tsixtm1Jtl
involves: 129S4/SvJae 		normal cellular phenotype J:57967
Tsixtm2Jtl/Y
involves: 129 * M. m. castaneus 		abnormal dosage compensation, by inactivation of X chromosome J:57967
abnormal imprinting J:57967
Tsixtm2Jtl/Tsix+
involves: 129 * M. m. castaneus 		abnormal dosage compensation, by inactivation of X chromosome J:57967
abnormal imprinting J:57967
prenatal lethality J:57967
Tsixtm3Jtl/Tsix+
involves: 129 		abnormal imprinting J:117335
decreased litter size J:117335
decreased survivor rate J:117335
embryonic lethality at implantation, incomplete penetrance J:117335
Tsixtm3Jtl/Y
involves: 129 		abnormal imprinting J:117335
decreased survivor rate J:117335
embryonic lethality at implantation, incomplete penetrance J:117335
Tsixtm3Jtl/Tsixtm3Jtl
involves: 129 		prenatal lethality, complete penetrance J:117335
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory