Fkbp1b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fkbp1b
FK506 binding protein 1b
MGI:1336205

19 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fkbp1b^tm1.1Okam/Fkbp1b^tm1.1Okam ICR.129-Fkbp1b^tm1.1Okam	decreased insulin secretion	J:136192
	normal homeostasis/metabolism phenotype	J:136192
	impaired glucose tolerance	J:136192
Fkbp1b^tm1Amks/Fkbp1b^tm1Amks DBA/1LacJ-Fkbp1b^tm1Amks	irregular heartbeat	J:107733
	premature death	J:107733
	ventricular tachycardia	J:107733
Fkbp1b^tm1Amks/Fkbp1b^tm1Amks involves: DBA/1LacJ	atrial fibrillation	J:212640
Fkbp1b^{tm1b(EUCOMM)Hmgu}/Fkbp1b^{tm1b(EUCOMM)Hmgu} C57BL/6N-Fkbp1b^{tm1b(EUCOMM)Hmgu}/BayMmucd	abnormal retina blood vessel morphology	J:211773
	increased startle reflex	J:211773
Fkbp1b^tm1Syf/Fkbp1b^tm1Syf either: (involves: 129S/SvEv) or (involves: 129S/SvEv * C57BL/6)	abnormal interventricular septum morphology	J:75646
	abnormal myocardial fiber physiology	J:75646
	cardiac hypertrophy	J:75646
	hypertension	J:75646
	increased heart left ventricle posterior wall thickness	J:75646
	increased heart left ventricle weight	J:75646
	increased heart weight	J:75646
	increased systemic arterial diastolic blood pressure	J:75646
	increased systemic arterial systolic blood pressure	J:75646
	thick interventricular septum	J:75646

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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