Mocs2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mocs2
molybdenum cofactor synthesis 2
MGI:1336894

35 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mocs2^{tm1(KOMP)Vlcg}/Mocs2⁺ involves: C57BL/6NTac	increased neuron apoptosis	J:242197
Mocs2^{tm1(KOMP)Vlcg}/Mocs2^{tm1(KOMP)Vlcg} involves: C57BL/6NTac	abnormal blood homeostasis	J:242197
	abnormal enzyme/coenzyme activity	J:242197
	abnormal hair growth	J:242197
	abnormal kidney collecting duct morphology	J:242197
	abnormal kidney pelvis morphology	J:242197
	abnormal vibrissa morphology	J:242197
	curly vibrissae	J:242197
	cystinuria	J:242197
	cystolithiasis	J:242197
	decreased blood uric acid level	J:242197
	decreased body size	J:242197
	decreased urine uric acid level	J:242197
	erythrocyturia	J:242197
	flaky skin	J:242197
	hemoglobinuria	J:242197
	increased circulating creatinine level	J:242197
	increased neuron apoptosis	J:242197
	increased urine hypoxanthine level	J:242197
	increased urine protein level	J:242197
	increased urine xanthine level	J:242197
	ischuria	J:242197
	kidney failure	J:242197
	muscle weakness	J:242197
	nephrolithiasis	J:242197
	postnatal growth retardation	J:242197
	postnatal lethality, complete penetrance	J:242197
	slow postnatal weight gain	J:242197
	urinary bladder obstruction	J:242197
	weakness	J:242197
	wrinkled skin	J:242197
Mocs2^{tm1b(EUCOMM)Wtsi}/Mocs2⁺ C57BL/6N-Mocs2^{tm1b(EUCOMM)Wtsi}/Ieg	decreased body length	J:211773
	decreased circulating sodium level	J:211773
	increased fasting circulating glucose level	J:211773
	persistence of hyaloid vascular system	J:211773
Mocs2^{tm1b(EUCOMM)Wtsi}/Mocs2^{tm1b(EUCOMM)Wtsi} C57BL/6N-Mocs2^{tm1b(EUCOMM)Wtsi}/Ieg	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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