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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Trp73
transformation related protein 73
MGI:1336991
21 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atmtm1Pmc/Atmtm1Pmc
Trp73tm2Mak/Trp73tm2Mak
involves: 129P2/OlaHsd * C57BL/6J 		decreased cellular sensitivity to gamma-irradiation J:157905
decreased thymocyte apoptosis J:157905
Gt(ROSA)26Sortm1(DTA)Riet/Gt(ROSA)26Sor+
Relnrl/Reln+
Trp73tm1(cre)Agof/Trp73+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		decreased Cajal-Retzius cell number J:153209
Gt(ROSA)26Sortm1(DTA)Riet/Gt(ROSA)26Sor+
Relnrl/Reln+
Trp73tm1(cre)Agof/Trp73+
Wnt3atm1(cre)Eag/Wnt3a+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		decreased Cajal-Retzius cell number J:153209
Gt(ROSA)26Sortm1(DTA)Riet/Gt(ROSA)26Sor+
Trp73tm1(cre)Agof/Trp73+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		decreased Cajal-Retzius cell number J:153209
Trp53tm1Brd/Trp53tm1Brd
Trp73tm2Mak/Trp73tm2Mak
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J 		decreased cellular sensitivity to gamma-irradiation J:157905
decreased thymocyte apoptosis J:157905
Trp53tm1Tyj/Trp53+
Trp73tm1Fmc/Trp73+
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 		increased hepatocellular carcinoma incidence J:98958
increased lung adenocarcinoma incidence J:98958
increased metastatic potential J:98958
increased pancreatic acinar cell carcinoma incidence J:98958
increased sarcoma incidence J:98958
increased T cell derived lymphoma incidence J:98958
increased tumor incidence J:98958
premature death J:98958
Trp63tm1Fmc/Trp63+
Trp73tm1Fmc/Trp73+
involves: 129S4/SvJae * C57BL/6 		increased carcinoma incidence J:98958
increased chronic myelocytic leukemia incidence J:98958
increased hemangiosarcoma incidence J:98958
increased lung adenocarcinoma incidence J:98958
increased lung adenoma incidence J:98958
increased mammary adenocarcinoma incidence J:98958
increased metastatic potential J:98958
increased salivary gland adenoma incidence J:98958
increased squamous cell carcinoma incidence J:98958
increased T cell derived lymphoma incidence J:98958
increased tumor incidence J:98958
intervertebral disk degeneration J:98958
paralysis J:98958
premature aging J:98958
premature death J:98958
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory