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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ncor2
nuclear receptor co-repressor 2
MGI:1337080
72 phenotypes from 6 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ncor2em1(IMPC)Mbp/Ncor2+
C57BL/6N-Ncor2em1(IMPC)Mbp/MbpMmucd 		abnormal blood vessel morphology J:211773
abnormal placenta morphology J:211773
abnormal retina morphology J:211773
embryonic growth retardation J:211773
persistence of hyaloid vascular system J:211773
Ncor2em1(IMPC)Mbp/Ncor2em1(IMPC)Mbp
C57BL/6N-Ncor2em1(IMPC)Mbp/MbpMmucd 		abnormal blood vessel morphology J:211773
abnormal craniofacial morphology J:211773
abnormal placenta morphology J:211773
abnormal placenta vasculature J:211773
edema J:211773
preweaning lethality, complete penetrance J:211773
Ncor2Gt(RRM275)Byg/Ncor2+
B6.129P2-Ncor2Gt(RRM275)Byg 		abnormal cell differentiation J:164558
abnormal eating behavior J:164558
abnormal hormone level J:164558
abnormal white adipose tissue physiology J:164558
decreased carbon dioxide production J:164558
decreased circulating insulin level J:164558
decreased circulating leptin level J:164558
decreased energy expenditure J:164558
decreased oxygen consumption J:164558
decreased susceptibility to diet-induced hepatic steatosis J:164558
decreased white fat cell size J:164558
increased insulin sensitivity J:164558
increased susceptibility to diet-induced obesity J:164558
increased white adipose tissue amount J:164558
increased white fat cell number J:164558
Ncor2Gt(RRM275)Byg/Ncor2Gt(RRM275)Byg
B6.129P2-Ncor2Gt(RRM275)Byg 		prenatal lethality, complete penetrance J:164558
Ncor2tm1.1Ics/Ncor2tm1.1Ics
involves: 129S2/SvPas * C57BL/6J 		normal liver/biliary system phenotype J:206152
Ncor2tm1Rev/Ncor2tm1Rev
involves: 129/Sv * C57BL/6 		abnormal bone marrow cavity morphology J:202976
abnormal bone marrow cell number J:202976
abnormal bone marrow morphology J:202976
abnormal cell differentiation J:142665
abnormal circulating enzyme level J:202976
abnormal circulating hormone level J:202976
abnormal gas homeostasis J:142665
abnormal gluconeogenesis J:142665
abnormal hematopoietic stem cell morphology J:202976
abnormal metabolism J:142665
abnormal physiological response to xenobiotic J:142665
abnormal skeleton physiology J:202976
abnormal spleen morphology J:202976
abnormal trabecular bone morphology J:202976
normal adipose tissue phenotype J:142665
decreased body temperature J:142665
decreased body weight J:142665
decreased bone strength J:202976
decreased carbon dioxide production J:142665
decreased compact bone thickness J:202976
decreased energy expenditure J:142665
decreased oxygen consumption J:142665
enlarged spleen J:202976
extramedullary hematopoiesis J:202976
hindlimb paresis J:202976
increased adiponectin level J:142665
increased bone trabecula number J:202976
increased circulating glucose level J:142665
increased epididymal fat pad weight J:142665
increased erythroid progenitor cell number J:202976
increased megakaryocyte cell number J:202976
increased osteoclast cell number J:202976
increased percent body fat/body weight J:142665
increased trabecular bone volume J:202976
insulin resistance J:142665
myelofibrosis J:202976
normal nervous system phenotype J:142665
osteosclerosis J:202976
thin ventricular wall J:142665
Ncor2tm1Rsd/Ncor2tm1Rsd
involves: 129S1/Sv * 129X1/SvJ 		abnormal heart development J:127720
abnormal neuronal precursor proliferation J:127720
abnormal telencephalon morphology J:127720
lethality throughout fetal growth and development, complete penetrance J:127720
thin ventricular wall J:132982
ventricular septal defect J:132982
Ncor2tm1Rsd/Ncor2tm1Rsd
Tg(Myh6-Ncor2)1Kjep/?
involves: 129/Sv * BALB/c * C57BL/6 		abnormal cerebral cortex morphology J:127720
abnormal telencephalon development J:127720
cleft secondary palate J:127720
normal mortality/aging J:127720
palatal shelves fail to meet at midline J:127720
thin cortical plate J:127720
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory