Eya4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Eya4
EYA transcriptional coactivator and phosphatase 4
MGI:1337104

21 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Eya4^{TgTn(Prm1-sb10,sb-Tyr)1739AOve}/Eya4^{TgTn(Prm1-sb10,sb-Tyr)1739AOve} involves: C57BL/6 * FVB	cleft palate	J:175597
	neonatal lethality, complete penetrance	J:175597
Eya4^{tm1b(KOMP)Wtsi}/Eya4⁺ C57BL/6N-Eya4^{tm1b(KOMP)Wtsi}/Tcp	edema	J:211773
	small adrenal glands	J:211773
Eya4^{tm1b(KOMP)Wtsi}/Eya4^{tm1b(KOMP)Wtsi} C57BL/6N-Eya4^{tm1b(KOMP)Wtsi}/Tcp	abnormal embryo size	J:211773
	edema	J:211773
	preweaning lethality, complete penetrance	J:211773
Eya4^tm1Jse/Eya4^tm1Jse 129S6/SvEvTac-Eya4^tm1Jse	postnatal lethality, complete penetrance	J:131873
Eya4^tm1Jse/Eya4^tm1Jse involves: 129S6/SvEvTac * CBA/J	abnormal auditory brainstem response	J:131873
	abnormal auditory tube morphology	J:131873
	abnormal distortion product otoacoustic emission	J:131873
	abnormal middle ear epithelium morphology	J:131873
	abnormal palate bone morphology	J:131873
	abnormal tympanic cavity morphology	J:131873
	abnormal tympanic membrane morphology	J:131873
	decreased body weight	J:131873
	increased middle ear goblet cell number	J:131873
	increased susceptibility to otitis media	J:131873
	male infertility	J:131873
	middle ear effusion	J:131873
	middle ear polyps	J:131873
	postnatal lethality, complete penetrance	J:131873
	tympanic membrane retraction	J:131873

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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