About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rev3l
REV3 like, DNA directed polymerase zeta catalytic subunit
MGI:1337131
11 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
Rev3ltm1.1Diaz/Rev3ltm1.1Diaz
Cd19tm1(cre)Cgn/Cd19+
involves: 129P2/OlaHsd * 129X1/SvJ * BALB/c * C57BL/6 * C57BL/6NTac 		abnormal class switch recombination J:188723
abnormal somatic hypermutation frequency J:188723
decreased B cell proliferation J:188723
normal immune system phenotype J:188723
Rev3ltm1Ndew/Rev3ltm1Ndew
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 		abnormal embryonic tissue morphology J:75450
embryonic lethality during organogenesis, complete penetrance J:75450
Rev3ltm1Rwd/Rev3ltm2.1Rwd
Trp53tm1Brd/Trp53+
Tg(MMTV-cre)1Mam/0
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * FVB/N 		increased carcinoma incidence J:158922
increased mammary gland tumor incidence J:158922
increased osteosarcoma incidence J:158922
Rev3ltm1Rwd/Rev3ltm2.1Rwd
Trp53tm1Brd/Trp53tm1Brd
Tg(MMTV-cre)1Mam/0
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * FVB/N 		increased T cell derived lymphoma incidence J:158922
premature death J:158922
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory